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Gene Review

4CL1  -  4-coumarate:coenzyme A ligase

Glycine max

 
 
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High impact information on 4CL1

  • In contrast, divergent members of a 4CL gene family were identified in soybean (Glycine max L.). We isolated three structurally and functionally distinct 4CL cDNAs encoding 4CL1, 4CL2, and 4CL3 and the gene Gm4CL3 [1].
  • Surprisingly, the activity levels of the four isoenzymes and steady-state levels of their transcripts were differently affected after elicitor treatment of soybean cell cultures with a beta-glucan elicitor of Phytophthora sojae, revealing the down-regulation of 4CL1 vs. up-regulation of 4CL3/4 [1].
  • Remarkably, one isoenzyme (4CL1) was able to convert sinapate; thus the first cDNA encoding a 4CL that accepts highly substituted cinnamic acids is available for further studies on branches of phenylpropanoid metabolism that probably lead to the precursors of lignin [1].

References

  1. Divergent members of a soybean (Glycine max L.) 4-coumarate:coenzyme A ligase gene family. Lindermayr, C., Möllers, B., Fliegmann, J., Uhlmann, A., Lottspeich, F., Meimberg, H., Ebel, J. Eur. J. Biochem. (2002) [Pubmed]
 
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