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Gene Review

stx3  -  syntaxin 3

Xenopus (Silurana) tropicalis

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High impact information on stx3

  • In this study, we show that syntaxin 1A, but not syntaxin 3 or 4, inhibited whole cell ROMK currents in Xenopus laevis oocytes [1].
  • Coexpression of CFTR with syntaxin 1A, but not syntaxin 3, inhibited cAMP-induced increases in membrane capacitance and plasma membrane CFTR content [2].


  1. Inhibition of ROMK potassium channel by syntaxin 1A. Sun, T.J., Zeng, W.Z., Huang, C.L. Am. J. Physiol. Renal Physiol. (2005) [Pubmed]
  2. Syntaxin 1A inhibits regulated CFTR trafficking in xenopus oocytes. Peters, K.W., Qi, J., Watkins, S.C., Frizzell, R.A. Am. J. Physiol. (1999) [Pubmed]
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