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Rhcg  -  Rhesus blood group-associated C glycoprotein

Mus musculus

Synonyms: Ammonium transporter Rh type C, BB065800, Rh family type C glycoprotein, Rh type C glycoprotein, Rhesus blood group family type C glycoprotein, ...
 
 
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High impact information on Rhcg

  • In situ hybridization revealed strong expression of Rhcg in the kidney collecting tubules and testis seminiferous tubules [1].
  • Despite sharing a notable similarity to the erythroid forms, including the 12-transmembrane topological fold, the RHCG/Rhcg pair is distinct in chromosome location, genomic organization, promoter structure, and tissue-specific expression [1].
  • RHCG and Rhcg map at 15q25 of human chromosome 15 and the long arm of mouse chromosome 7, respectively, each having 11 exons and a CpG-rich promoter [1].
  • Recently, two non-erythroid Rh glycoproteins were cloned from mice (Rhcg and Rhbg) and humans (RhCG and RhBG) [2].
 

Anatomical context of Rhcg

  • These results pinpoint RhCG and Rhcg as novel polytopic membrane glycoproteins that may function as epithelial transporters maintaining normal homeostatic conditions in kidney and testis [1].
 

Associations of Rhcg with chemical compounds

  • Characterization of human RhCG and mouse Rhcg as novel nonerythroid Rh glycoprotein homologues predominantly expressed in kidney and testis [1].
 

Analytical, diagnostic and therapeutic context of Rhcg

References

 
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