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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Pkp3  -  plakophilin 3

Mus musculus

Synonyms: 2310056L12Rik, Plakophilin-3
 
 
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High impact information on Pkp3

  • Together, these results show that PKP3, whose epithelial and epidermal desmosomal expression pattern and protein interaction repertoire are broader than those of PKP1 and -2, is a unique multiprotein binding element in the basic architecture of a vast majority of epithelial desmosomes [1].
  • Western blot analysis of plakophilin-3 revealed expression in all epithelial cell lines tested but not in foreskin fibroblasts and various sarcoma-derived cell lines [2].
 

Analytical, diagnostic and therapeutic context of Pkp3

References

  1. Defining desmosomal plakophilin-3 interactions. Bonné, S., Gilbert, B., Hatzfeld, M., Chen, X., Green, K.J., van Roy, F. J. Cell Biol. (2003) [Pubmed]
  2. Plakophilin-3, a novel armadillo-like protein present in nuclei and desmosomes of epithelial cells. Bonné, S., van Hengel, J., Nollet, F., Kools, P., van Roy, F. J. Cell. Sci. (1999) [Pubmed]
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