Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

Phax - phosphorylated adaptor for RNA export

Mus musculus

Synonyms: 2810055C14Rik, 4933427L19Rik, AU018701, AU018854, D18Ertd65e, ...

Cheng, S.H. et al., Eide, E.J. et al., Parvathy, S. et al., Wiedłocha, A. et al.

Wiedłocha, Nilsen, Wesche, Sørensen, Małecki, Marcinkowska, Olsnes,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Rnuxa

Although phosphorylation-regulated proteolysis of these inhibitors is postulated to be essential for the function of the clock, inhibition of this process has not yet been shown to alter mammalian circadian rhythm [1].
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1 [2].
Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding [3].
Because earlier studies showed delta F508-CFTR retains significant phosphorylation-regulated chloride (Cl-) channel activity, processes capable of restoring the mislocalized delta F508-CFTR to the correct cellular destination may have therapeutic benefit [4].

References

Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. Eide, E.J., Woolf, M.F., Kang, H., Woolf, P., Hurst, W., Camacho, F., Vielhaber, E.L., Giovanni, A., Virshup, D.M. Mol. Cell. Biol. (2005) [Pubmed]
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1. Wiedłocha, A., Nilsen, T., Wesche, J., Sørensen, V., Małecki, J., Marcinkowska, E., Olsnes, S. Mol. Biol. Cell (2005) [Pubmed]
Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding. Parvathy, S., Ehrlich, M., Pedrini, S., Diaz, N., Refolo, L., Buxbaum, J.D., Bogush, A., Petanceska, S., Gandy, S. J. Neurochem. (2004) [Pubmed]
Functional activation of the cystic fibrosis trafficking mutant delta F508-CFTR by overexpression. Cheng, S.H., Fang, S.L., Zabner, J., Marshall, J., Piraino, S., Schiavi, S.C., Jefferson, D.M., Welsh, M.J., Smith, A.E. Am. J. Physiol. (1995) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

PHAX	Bos taurus
PHAX	Canis lupus familiaris
phax	Danio rerio
PHAX	Gallus gallus
PHAX	Homo sapiens
PHAX	Macaca mulatta
PHAX	Pan troglodytes
Phax	Rattus norvegicus
phax	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share