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Gene Review

Slc16a8  -  solute carrier family 16 (monocarboxylic...

Mus musculus

Synonyms: MCT 3, Mct3, Monocarboxylate transporter 3, Proton-coupled monocarboxylate transporter 3, Solute carrier family 16 member 8, ...
 
 
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High impact information on Slc16a8

  • Mouse MCT3 gene is expressed preferentially in retinal pigment and choroid plexus epithelia [1].
  • In chicken, MCT3 is preferentially expressed in the retinal pigment epithelium (RPE) [1].
  • Immunohistochemical staining demonstrated that MCT3 was restricted to the basolateral membranes of both epithelia but was more abundant in RPE than CPE [1].
  • The cloning of MCT3 identifies a specific transporter that could regulate lactate levels in fluid-bathing neuronal tissues [1].
  • Based on Northern hybridization analysis, MCT3 transcript was expressed in only two tissues: RPE and choroid plexus epithelium (CPE) [1].

References

  1. Mouse MCT3 gene is expressed preferentially in retinal pigment and choroid plexus epithelia. Philp, N.J., Yoon, H., Lombardi, L. Am. J. Physiol., Cell Physiol. (2001) [Pubmed]
 
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