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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Mapk8ip2  -  mitogen-activated protein kinase 8...

Mus musculus

Synonyms: 3230402N03Rik, AI847694, AW049958, C-Jun-amino-terminal kinase-interacting protein 2, IB-2, ...
 
 
 
 
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High impact information on Mapk8ip2

  • Finally, of the three scaffold proteins of the JIP family expressed in brown adipocytes, only JIP2 co-immunoprecipitates p38alpha MAPK and MKK3 [1].
  • Therefore, in the brown adipocyte the recently described scaffold protein JIP2 assembles the required factors MKK3 and p38alpha MAPK linking PKA to the control of thermogenic gene expression [1].

References

  1. Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes. Robidoux, J., Cao, W., Quan, H., Daniel, K.W., Moukdar, F., Bai, X., Floering, L.M., Collins, S. Mol. Cell. Biol. (2005) [Pubmed]
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