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Gene Review:

D6Mit55 - DNA segment, Chr 6, Massachusetts...

Mus musculus

Ko, C. et al., McKee-Johnson, J.W. et al., Street, V.A. et al.

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High impact information on D6Mit55

The first locus, designated Abrg1, was mapped to chromosome 6 in 8-week-old male and female mice with a combined logarithm of odds ratio (LOD) score of 14 at the D6Mit55 marker ( approximately 45.9 cM) [1].
A yeast artificial chromosome-based physical map suggests that the closest markers flanking the dfw locus, D6Mit11 (proximal) and Gat4, D6Mit55 (distal), are contained within 650-950 kb [2].
Analysis of the backcross progeny positioned the dfw locus in the interval between the microsatellite markers D6Mit11 and D6Mit55, D6Mit63 [3].

References

Two novel quantitative trait loci on mouse chromosomes 6 and 4 independently and synergistically regulate plasma apoB levels. Ko, C., Lee, T.L., Lau, P.W., Li, J., Davis, B.T., Voyiaziakis, E., Allison, D.B., Chua, S.C., Huang, L.S. J. Lipid Res. (2001) [Pubmed]
Physical and genetic maps of the deafwaddler region on distal mouse Chr 6. McKee-Johnson, J.W., Street, V.A., Erford, S.K., Robinson, L.C., Tempel, B.L. Genomics (1998) [Pubmed]
Molecular genetic analysis of distal mouse chromosome 6 defines gene order and positions of the deafwaddler and opisthotonos mutations. Street, V.A., Robinson, L.C., Erford, S.K., Tempel, B.L. Genomics (1995) [Pubmed]

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