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Gene Review

D5Mit267  -  DNA segment, Chr 5, Massachusetts...

Mus musculus

 
 
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High impact information on D5Mit267

  • Using SSLP markers, we have mapped the tilted (tlt) gene on mouse Chromosome (Chr) 5 between D5Mit421 and D5Mit353/D5Mit128/D5Mit266/D5Mit267 by analysis of the progeny of an intersubspecific F2 intercross [1].
  • The recessive effect was observed also at D1Mit67, D5Mit267, D6Mit384 and D19Mit33, suggesting the presence of genes for accelerated senescence in the SAMP strains around these loci [2].

References

  1. High-resolution mapping of tlt, a mouse mutant lacking otoconia. Ying, H.C., Hurlé, B., Wang, Y., Bohne, B.A., Wuerffel, M.K., Ornitz, D.M. Mamm. Genome (1999) [Pubmed]
  2. Genetic analysis of lifespan in hybrid progeny derived from the SAMP1 mouse strain with accelerated senescence. Guo, Z., Toichi, E., Hosono, M., Hosokawa, T., Hosokawa, M., Higuchi, K., Mori, M. Mech. Ageing Dev. (2000) [Pubmed]
 
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