Disease relevance of SVD

• There was no significant correlation between SVD and delta %cbll or MVD and delta %cbll in the patients with cerebral infarction [1].
• The present study introduces new parameters of segmental myocardial function that might be helpful in predicting SVD and MVD in patients after myocardial infarction [2].
• In conclusion, patients with SVD after myocardial infarction display compensatory hyperkinesis of remote segments, which is attenuated in patients with MVD [2].
• Acute-phase serology was useful in designating inflammatory processes at presentation of patients presenting with encephalopathy caused by SVD only, but were unhelpful in defining relapses in this form of PACNS, the definition of which in all cases rested on clinical assessment and MR scanning [3].
• Seven of the 20 patients changed from LSD to SVD and vice-versa on 3 occasions, and in all cases, we found an increase of proteinuria during the LSD period [4].

Psychiatry related information on SVD

• These results show that neuropsychological tests can distinguish SVD and MD from AD with high sensitivity (88-94%) [5].
• This study examined the neuropsychological profile of probable Alzheimer's disease (AD, n=72), vascular dementia due to diffuse subcortical small vessel disease (SVD, n=18) and mixed dementia (AD+SVD, n=18) [5].
• A sex-by-type of death interaction occurred for locus of control, with SVD females being the most external, suggesting that this group was more likely to "give up" in response to stress [6].

High impact information on SVD

• BACKGROUND: Sinus venosus atrial septal defect (SVD) is underdiagnosed with transthoracic echocardiography because of its posterior (far field) location [7].
• The spatial and temporal response components were extracted and validated by comparison to results from traditional SVD/PCA analyses based on scenarios of unfolding into lower-order bilinear structures [8].
• SETTING: These studies took place at the University of Nottingham Medical School. RESULTS: I(Ca(T)) of both SVD and CS cells were blocked by nickel (IC(50) of 5.6 microm) and cobalt chloride (1 mm) but unaffected by nifedipine (10 microm) [9].
• DESIGN: The nystatin-perforated patch-clamp technique was used to record inward T-type calcium current (I(Ca(T))) from acutely dispersed decidual stromal cells obtained from women at either elective cesarean section [CS (nonlabor)] or after normal spontaneous vaginal delivery [SVD (labor)] [9].
• When PACNS was divided into small- and middle-sized vessel disease (SVD/MVD), their clinical courses differed substantially [3].

Chemical compound and disease context of SVD

• Proteinuria, daily urea nitrogen excretion and creatinine clearance decreased significantly on SVD [4].

Biological context of SVD

• We compared simultaneous measurements of stroke volume by direct Fick (SVF) and noninvasive pulsed Doppler (SVD) techniques in 15 resting, supine cardiac patients [10].
• The patient underwent SVD, or spontaneous vaginal delivery at 36 weeks gestation with respective weights and apgars of 2673 g (apgars 7(1), 9(5)) and 2722 g (apgars 7(1), 9(5)) [11].
• As an example of the need for the procedures we recommend in this communication, we have chosen an important case in point that has been published recently, and which deals with the kinetics of electron transfer from fully-reduced cytochrome oxidase to O2, analyzed by the method of SVD-based least squares [12].
• Since different degrees of exercise tolerance were found in pts with SVD, DVD and TVD, we hypothesize that the correlation between delta R and the severity of CAD at the end of stress testing may be artifactual [13].
• For the first time to our knowledge, we report this association not only for LVD and SVD but also for cryptogenic stroke, implying that future studies of the genetics of ischemic stroke should target these 3 subtypes [14].

Anatomical context of SVD

• Cyclic AMP was 29.8 +/- 1.5, 39.6 +/- 8.0, and 35.9 +/- 3.9 pmoles/100 mg tissue in SVD, OXIL, and ECS placentas, respectively [15].
• The results showed 1,175 spleens (98%) with SVD at the hilum of < 8 mm and 25 spleens (2%) with SVD of > 8 mm [16].
• 60 with SVD underwent a wrist-enhanced, minimally invasive direct coronary artery bypass procedure [17].
• Of the CAD patients, 17 had coronary lesions associated with a limited area of underperfused myocardium (seven with good collateral circulation and 10 with distal lesions) (MILD), 15 patients exhibited a proximal lesion in a single vessel (SVD), and 15 patients had significant multivessel disease (MVD) [18].

Associations of SVD with chemical compounds

• Thus tissue concentrations of progesterone, estradiol-17 beta, and cyclic adenosine monophosphate (AMP) were measured in placentas obtained after spontaneous vaginal delivery (SVD, N = 11), after oxytocin-induced labor (OXIL, N = 5), and at elective cesarean section (ECS, N = 8) [15].
• A similar lowering effect of SVD was observed on serum total cholesterol [4].
• In this study, 20 steroid-resistant, nephrotic patients were treated with a pure vegetarian, low-protein diet, supplemented with essential amino acids and ketoanalogues (supplemented vegan diet, SVD) for 4.6 +/- 3.1 months [4].

Other interactions of SVD

• Twenty-three of 25 patients (92%) with enlarged SVD had recent histories of hematopoietic or infectious diseases [16].
• There were three valve-related deaths of a total of ten deaths (early 2; late 1) (TE 2; ATH 1; CVD 0; PVE 0; PPL 0; and SVD 0) [19].
• There were 28 valve-related deaths of a total 280 deaths (early 4, late 24) (TE 17; ATH 3; CVD 1; PVE 7; PPL 0; and SVD 0) [20].

Analytical, diagnostic and therapeutic context of SVD

• Prior transthoracic echocardiography clearly defined the SVD in 3 of these patients, and it was suspected in another 11 on the basis of color-flow imaging [7].
• METHODS AND RESULTS: A retrospective study was undertaken that used the medical history, echocardiographic findings, and surgical data of patients identified from computer records as having the diagnosis of SVD during the period in which TEE has been in use (1987 to 1995) [7].
• Transesophageal echocardiography (TEE) should be ideally suited to diagnose SVD, given the proximity of the transducer to the defect [7].
• Within this context of local regularization, we show that a generalized version of the singular value decomposition (GSVD) can further improve the accuracy of ECG inverse solutions compared to standard SVD and Tikhonov approaches [21].
• Both SPECT (SVD) and MRI volume deficit (MVD) were measured to examine their relationship with CCD [1].

References