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Gene Review

SFSWAP  -  splicing factor, suppressor of white...

Homo sapiens

Synonyms: SFRS8, SWAP, Splicing factor, arginine/serine-rich 8, Splicing factor, suppressor of white-apricot homolog, Suppressor of white apricot protein homolog
 
 
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High impact information on SFRS8

  • T cells are involved in the pathogenesis of atopic diseases such as asthma, so SFRS8 is a very interesting candidate gene in the region [1].
  • Three single nucleotide polymorphisms in splicing factor, arginine/serine-rich 8 (SFRS8) had an association with asthma (p</=0.0020-0.050) in a sample of 136 asthmatic sib pairs [1].
  • Significant linkage to chromosome 12q24.32-q24.33 and identification of SFRS8 as a possible asthma susceptibility gene [1].

References

  1. Significant linkage to chromosome 12q24.32-q24.33 and identification of SFRS8 as a possible asthma susceptibility gene. Brasch-Andersen, C., Tan, Q., B??rglum, A.D., Haagerup, A., Larsen, T.R., Vestbo, J., Kruse, T.A. Thorax (2006) [Pubmed]
 
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