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Gene Review:

LOC652956 - p55 protein

Rattus norvegicus

Jing-Ping, Z. et al., Elberg, G. et al., Barque, J.P. et al., Singh, B. et al.

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High impact information on LOC652956

After vanadate treatment, a phosphorylated P55 protein is immunoprecipitated by antibodies to both phosphotyrosine and phosphatidylinositol (PI) 3-kinase [1].
The P55 protein affected by v-mos expression is vimentin [2].
In this report, we show by immunoelectron microscopy that the p55 protein associates in situ with the chromatin of rat hepatocytes [3].
The interaction with PSD-95 was found to occur between the PDZ domains of PSD-95 and the HOOK and GK domains of r-p55 protein [4].
We investigated rat p55 (r-p55) in the brain. r-p55 mRNA was expressed widely in various tissues and in various regions of the brain. r-p55 protein was also expressed widely in various rat tissues, including brain and erythrocytes [4].

Other interactions of LOC652956

p55 is a membrane-associated guanylate kinase (MAGuK) family member that consists of a single PDZ followed by SH3, HOOK and guanylate kinase (GuK or GK) domains [4].

References

Vanadate activates membranous nonreceptor protein tyrosine kinase in rat adipocytes. Elberg, G., He, Z., Li, J., Sekar, N., Shechter, Y. Diabetes (1997) [Pubmed]
The P55 protein affected by v-mos expression is vimentin. Singh, B., Goldman, R., Hutton, L., Herzog, N.K., Arlinghaus, R.B. J. Virol. (1987) [Pubmed]
PSL, an S phase-related p55 nuclear antigen, associates transiently with chromatin. Barque, J.P., Lagaye, S., Bendayan, M., Puvion-Dutilleul, F., Danon, F., Larsen, C.J. Exp. Cell Res. (1985) [Pubmed]
p55 protein is a member of PSD scaffold proteins in the rat brain and interacts with various PSD proteins. Jing-Ping, Z., Tian, Q.B., Sakagami, H., Kondo, H., Endo, S., Suzuki, T. Brain Res. Mol. Brain Res. (2005) [Pubmed]

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