Gene Review:
F11R - F11 receptor
Felis catus
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Disease relevance of JAM-1
- Junctional adhesion molecule 1 is a functional receptor for feline calicivirus [1].
High impact information on JAM-1
- In Vero cells, an anti-human JAM-1 antibody inhibited binding, CPE, and progeny production by F4 and F25 [1].
- Taken together, our results demonstrate that feline JAM-1 is a functional receptor for FCV, simian JAM-1 also functions as a receptor for some strains of FCV, and the interaction between FCV and JAM-1 molecules may be a determinant of viral tropism [1].
References
- Junctional adhesion molecule 1 is a functional receptor for feline calicivirus. Makino, A., Shimojima, M., Miyazawa, T., Kato, K., Tohya, Y., Akashi, H. J. Virol. (2006) [Pubmed]
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