The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

Gkn1  -  gastrokine 1

Mus musculus

Synonyms: 18 kDa antrum mucosa protein, 2200002K21Rik, AMP-18, Amp18, BRICD1, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on Gkn1

  • We suggest that AMP-18 is a "gastrokine" that maintains the integrity of the gastric mucosal epithelium [1].
  • Peptide fragments of AMP-18, a novel secreted gastric antrum mucosal protein, are mitogenic and motogenic [2].
  • Release of the protein appears to be regulated because forskolin decreased the amount of immunoreactive AMP-18 in primary cultures of canine antrum mucosal epithelial cells, and indomethacin gavaged into the stomach of mice reduced AMP-18 content in antrum mucosal tissue before inducing histological injury [2].

References

  1. A novel mitogenic protein that is highly expressed in cells of the gastric antrum mucosa. Martin, T.E., Powell, C.T., Wang, Z., Bhattacharyya, S., Walsh-Reitz, M.M., Agarwal, K., Toback, F.G. Am. J. Physiol. Gastrointest. Liver Physiol. (2003) [Pubmed]
  2. Peptide fragments of AMP-18, a novel secreted gastric antrum mucosal protein, are mitogenic and motogenic. Toback, F.G., Walsh-Reitz, M.M., Musch, M.W., Chang, E.B., Del Valle, J., Ren, H., Huang, E., Martin, T.E. Am. J. Physiol. Gastrointest. Liver Physiol. (2003) [Pubmed]
 
WikiGenes - Universities