The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

Pacrg  -  PARK2 co-regulated

Mus musculus

Synonyms: 1700008H23Rik, Hypertension-related protein 1-like protein, PARK2 coregulated gene protein, Parkin coregulated gene protein homolog
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Pacrg

 

High impact information on Pacrg

  • In addition, the expression pattern of Pacrg during spermiogenesis suggests that it plays a role in sperm differentiation [1].
  • We show that Pacrg is highly expressed in the testes in both mice and humans [1].
  • Immunolocalization experiments on isolated spermatozoa show that the Pacrg protein is present in mature sperm [1].
  • The quaking mutation is a deletion of approximately 1.17 Mb of mouse chromosome 17, resulting in the deletion of the entire promoter and first five coding exons of PRKN In addition, the recently described Parkin Co-Regulated Gene (PACRG) is completely deleted [2].
 

Associations of Pacrg with chemical compounds

  • It's a double knock-out! The quaking mouse is a spontaneous deletion of parkin and parkin co-regulated gene (PACRG) [2].

References

  1. Deletion of the Parkin coregulated gene causes male sterility in the quaking(viable) mouse mutant. Lorenzetti, D., Bishop, C.E., Justice, M.J. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  2. It's a double knock-out! The quaking mouse is a spontaneous deletion of parkin and parkin co-regulated gene (PACRG). Lockhart, P.J., O'Farrell, C.A., Farrer, M.J. Mov. Disord. (2004) [Pubmed]
 
WikiGenes - Universities