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Gene Review

Boll  -  bol, boule-like (Drosophila)

Mus musculus

Synonyms: 4930554P13Rik, 4930597B14Rik, Boule, Protein boule-like
 
 
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High impact information on Boll

  • The autosomal gene DAZL is a member of a family of genes (DAZL, DAZ, BOULE), all of which contain a consensus RNA binding domain and are expressed in germ cells [1].
  • In a directed tri-hybrid assay the strongest interaction was with the consensus (GUn)n. This motif is found in the 5' UTR of CDC25C whose homologue is thought to be the target of Boule, the Dazl homologue in flies [2].

References

  1. Absence of mDazl produces a final block on germ cell development at meiosis. Saunders, P.T., Turner, J.M., Ruggiu, M., Taggart, M., Burgoyne, P.S., Elliott, D., Cooke, H.J. Reproduction (2003) [Pubmed]
  2. The RNA-binding specificity of the mouse Dazl protein. Venables, J.P., Ruggiu, M., Cooke, H.J. Nucleic Acids Res. (2001) [Pubmed]
 
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