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Ehmt1  -  euchromatic histone methyltransferase 1

Mus musculus

Synonyms: 9230102N17Rik, D330003E03, Eu-HMTase1, Euchromatic histone-lysine N-methyltransferase 1, Euhmtase1, ...
 
 
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High impact information on Ehmt1

  • ESET, G9a, SUV39-h1, SUV39-h2, and Eu-HMTase are histone methyltransferases that catalyze H3-K9 methylation in mammalian cells [1].
  • Recently we reported that G9a forms a stoichiometric heteromeric complex with another SET-domain-containing molecule, GLP/Eu-HMTase1 [2].

References

  1. Histone H3-K9 methyltransferase ESET is essential for early development. Dodge, J.E., Kang, Y.K., Beppu, H., Lei, H., Li, E. Mol. Cell. Biol. (2004) [Pubmed]
  2. Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP. Ueda, J., Tachibana, M., Ikura, T., Shinkai, Y. J. Biol. Chem. (2006) [Pubmed]
 
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