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Gene Review

PRKRIP1  -  PRKR interacting protein 1 (IL11 inducible)

Homo sapiens

Synonyms: C114, FLJ13902, KRBOX3, PRKR-interacting protein 1
 
 
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Disease relevance of PRKRIP1

  • Furthermore, mutating several highly conserved residues (H-108, C-114, C-133, L-145, and Q-146) or deleting the C-terminal 18 amino acids of Vif, either of which severely impairs Vif function, does not abolish its incorporation into virions [1].
 

High impact information on PRKRIP1

  • The contributions of C114 to receptor function were investigated here using site-directed mutagenesis of C114 to serine [2].
  • 1. Cysteine 114 (C114) of the human dopamine D3 receptor is located at the helical face of transmembrane segment III (TMIII) near aspartate 110, a counterion for the amine group of catecholamines [2].

References

 
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