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Gene Review: 

ISPD  -  2-C-methyl-D-erythritol 4-phosphate...

Arabidopsis thaliana

Synonyms: 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLTRANSFERASE, 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL SYNTHASE, ATMEPCT, MCT, T8K22.20, ...
 
 
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High impact information on ISPD

  • (ecotype Columbia) expressing the antisense AtMECT gene, encoding 2- C-methyl- D-erythritol 4-phosphate cytidylyltransferase, were generated to elucidate the physiological role of the nonmevalonate pathway for production of ent-kaurene, the latter being the plastidic precursor of gibberellins [1].
  • These observations suggest that both AtMECT and DXR are important in the synthesis of isopentenyl diphosphate and dimethylallyl diphosphate and that ent-kaurene is mainly produced through the nonmevalonate pathway in the plastid [1].

References

  1. Antisense and chemical suppression of the nonmevalonate pathway affects ent-kaurene biosynthesis in Arabidopsis. Okada, K., Kawaide, H., Kuzuyama, T., Seto, H., Curtis, I.S., Kamiya, Y. Planta (2002) [Pubmed]
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