The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

HPT1  -  homogentisate phytyltransferase 1

Arabidopsis thaliana

Synonyms: ATHPT, F19F24.15, F19F24_15, HOMOGENTISATE PHYTYLTRANSFERASE, TOCOPHEROL PHYTYLTRANSFERASE, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of HPT1

 

High impact information on HPT1

  • Surprisingly subtle differences were observed between the tocopherol-deficient vte2 mutant and the wild type during high-light, salinity, and drought stresses [2].
  • Both biochemical and transcriptional analyses of vte2 seedlings indicate that nonenzymatic lipid peroxidation plays a significant role in modulating plant defense responses [3].
  • In the absence of pathogens, the phytoalexin camalexin accumulated in vte2 seedlings to levels 100-fold higher than in wild-type or vte1 seedlings [3].
  • However, vte2, and to a lesser extent vte1, exhibited dramatic phenotypes under low temperature (i.e., increased anthocyanin levels and reduced growth and seed production) [2].
  • The rapid reduction in photoassimilate export in vte2 coincides with callose deposition exclusively in phloem parenchyma transfer cell walls adjacent to the companion cell/sieve element complex [2].
 

Chemical compound and disease context of HPT1

 

Biological context of HPT1

  • Compared with the wild type, vte1 and vte2 had reduced rates of photoassimilate export as early as 6 h into low-temperature treatment, increased soluble sugar levels by 60 h, and increased starch and reduced photosynthetic electron transport rate by 14 d [2].
  • In this study, we describe the identification of conserved amino acid sequences within VTE2 and HGGT and the application of these conserved sequences for a motif analysis resulting in the discovery of a VTE2-paralog in the Arabidopsis genome [4].
 

Associations of HPT1 with chemical compounds

References

  1. Isolation and functional analysis of homogentisate phytyltransferase from Synechocystis sp. PCC 6803 and Arabidopsis. Collakova, E., DellaPenna, D. Plant Physiol. (2001) [Pubmed]
  2. Tocopherols play a crucial role in low-temperature adaptation and Phloem loading in Arabidopsis. Maeda, H., Song, W., Sage, T.L., Dellapenna, D. Plant Cell (2006) [Pubmed]
  3. Nonenzymatic lipid peroxidation reprograms gene expression and activates defense markers in Arabidopsis tocopherol-deficient mutants. Sattler, S.E., Mène-Saffrané, L., Farmer, E.E., Krischke, M., Mueller, M.J., Dellapenna, D. Plant Cell (2006) [Pubmed]
  4. Identification and characterization of an Arabidopsis homogentisate phytyltransferase paralog. Venkatesh, T.V., Karunanandaa, B., Free, D.L., Rottnek, J.M., Baszis, S.R., Valentin, H.E. Planta (2006) [Pubmed]
  5. Homogentisate phytyltransferase activity is limiting for tocopherol biosynthesis in Arabidopsis. Collakova, E., DellaPenna, D. Plant Physiol. (2003) [Pubmed]
  6. Vitamin E protects against photoinhibition and photooxidative stress in Arabidopsis thaliana. Havaux, M., Eymery, F., Porfirova, S., Rey, P., Dörmann, P. Plant Cell (2005) [Pubmed]
 
WikiGenes - Universities