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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SMO2-2  -  sterol 4-alpha-methyl-oxidase 2-2

Arabidopsis thaliana

Synonyms: ATSMO2, ATSMO2-2, Arabidopsis thaliana sterol 4-alpha-methyl-oxidase 2-2, F16P2.23, F16P2_23, ...
 
 
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High impact information on SMO2-1

  • Heterologous expression of AtSMO1 and AtSMO2 in a yeast erg25 ergosterol auxotroph, lacking SMO activity, restored growth and endogenous ergosterol synthesis [1].
  • Specific primers derived from both genomic sequence data and EST cDNA sequences were used to polymerase chain reaction amplify two full-length cDNA sequences (AtSMO1 and AtSMO2), 801 and 783 bp, respectively, from an Arabidopsis thaliana cDNA library [1].
  • To elucidate the precise functions of SMO1 and SMO2 gene families, we have reduced their expression by using a VIGS (virus-induced gene silencing) approach in Nicotiana benthamiana [2].

References

  1. Functional identification of sterol-4alpha-methyl oxidase cDNAs from Arabidopsis thaliana by complementation of a yeast erg25 mutant lacking sterol-4alpha-methyl oxidation. Darnet, S., Bard, M., Rahier, A. FEBS Lett. (2001) [Pubmed]
  2. Plant sterol biosynthesis: identification of two distinct families of sterol 4alpha-methyl oxidases. Darnet, S., Rahier, A. Biochem. J. (2004) [Pubmed]
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