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Gene Review:

CYP90D1 - 3-epi-6-deoxocathasterone 23-monooxygenase

Arabidopsis thaliana

Synonyms: cytochrome P450, family 90, polypeptide 1, subfamily D

Ohnishi, T. et al., Bancoş, S. et al.

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High impact information on CYP90D1

C-23 Hydroxylation by Arabidopsis CYP90C1 and CYP90D1 Reveals a Novel Shortcut in Brassinosteroid Biosynthesis [1].
Feedback control of the CYP90C1, CYP90D1, and CYP85A2 genes by brassinolide suggests that the corresponding enzymes might also participate in BR synthesis [2].

Biological context of CYP90D1

In vitro biochemical assays using insect cell-expressed proteins revealed that both CYP90C1 and CYP90D1 catalyze C-23 hydroxylation of various 22-hydroxylated BRs with markedly different catalytic efficiencies [1].

References

C-23 Hydroxylation by Arabidopsis CYP90C1 and CYP90D1 Reveals a Novel Shortcut in Brassinosteroid Biosynthesis. Ohnishi, T., Szatmari, A.M., Watanabe, B., Fujita, S., Bancos, S., Koncz, C., Lafos, M., Shibata, K., Yokota, T., Sakata, K., Szekeres, M., Mizutani, M. Plant Cell (2006) [Pubmed]
Regulation of transcript levels of the Arabidopsis cytochrome p450 genes involved in brassinosteroid biosynthesis. Bancoş, S., Nomura, T., Sato, T., Molnár, G., Bishop, G.J., Koncz, C., Yokota, T., Nagy, F., Szekeres, M. Plant Physiol. (2002) [Pubmed]

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