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Gene Review:

GCN2 - eIF2alpha kinase

Arabidopsis thaliana

Synonyms: ARABIDOPSIS THALIANA GENERAL CONTROL NON-REPRESSIBLE 2, ATGCN2, GENERAL CONTROL NON-REPRESSIBLE 2

Zhang, Y. et al.

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High impact information on AT3G59410

The AtGCN2 peptide sequence included adjacent protein kinase and histidyl tRNA synthetase-like domains and showed 45% sequence identity with the GCN2 peptide sequence in the protein kinase domain [1].
Expression of AtGCN2 in yeast gcn2 mutants complemented the mutation, enabling growth in the presence of sulfometuron methyl, an inhibitor of branched-chain amino acid biosynthesis, and 3-aminotriazole, an inhibitor of histidine biosynthesis [1].

Analytical, diagnostic and therapeutic context of AT3G59410

Molecular cloning of an arabidopsis homologue of GCN2, a protein kinase involved in co-ordinated response to amino acid starvation [1].

References

Molecular cloning of an arabidopsis homologue of GCN2, a protein kinase involved in co-ordinated response to amino acid starvation. Zhang, Y., Dickinson, J.R., Paul, M.J., Halford, N.G. Planta (2003) [Pubmed]

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