High impact information on FAR1

• The FAR1 locus encodes a novel nuclear protein specific to phytochrome A signaling [1].
• This phenotype implies a specific requirement for FAR1 in phyA signal transduction [1].
• The FAR1 gene defines a new multigene family, which consists of at least four genes in Arabidopsis [1].
• The FAR1 protein contains a predicted nuclear localization signal and is targeted to the nucleus in transient transfection assays [1].
• The far1 locus maps to the south arm of chromosome 4, and is not allelic to photomorphogenic loci identified previously [1].

Biological context of FAR1

• There are 12 additional FHY3/FAR1-related genes in the Arabidopsis genome [2].
• The FHY3 and FAR1 genes encode transposase-related proteins involved in regulation of gene expression by the phytochrome A-signaling pathway [3].
• Moreover, overexpression of partial fragments of FHY3 can cause a dominant-negative interference phenotype on phyA signaling that is stronger than those of the fhy3 or far1 null mutants [4].

Physical interactions of FAR1

• Arabidopsis FHY3 defines a key phytochrome A signaling component directly interacting with its homologous partner FAR1 [4].

Other interactions of FAR1

• Our data indicate that FHY3, together with FAR1, defines a key module in a signaling network underlying phyA-mediated FR light responses [4].

References