High impact information on ABP1

• These results support a role of ABP1 as an auxin receptor controlling plant growth [1].
• Similarly, constitutive expression of maize ABP1 in maize cell lines conferred on them the capacity to respond to auxin by increasing cell size [1].
• The complete lack of auxin-inducible elongation in individual cells confirms the results observed in embryos, indicates a cell autonomous function, and, taken together with biochemical evidence that ABP1 binds auxins, suggests that ABP1 mediates auxin-induced cell elongation and, directly or indirectly, cell division [2].
• ABP1 is required for organized cell elongation and division in Arabidopsis embryogenesis [2].
• The affinity and specificity of TIR1 match properties anticipated of a nuclear auxin receptor and we look at how they compare with the properties of ABP1 [3].

Biological context of ABP1

• Antisense suppression of ABP1 in tobacco cells causes slow proliferation and eliminates auxin-induced cell elongation and reduces cell division [2].
• The ABP gene consisted of 5 exons and 4 introns and encoded a polypeptide of 198 residues [4].
• Within a defined window of leaf development, juvenile leaf cells that inducibly expressed Arabidopsis ABP1 prematurely advanced nuclei to the G2 phase [5].
• A sequence located within the 3'-half of the maize cDNA is highly repeated in the strawberry genome, from which clones with homology to both halves of the maize cDNA (i.e. putative ABP genes) have been isolated [6].

Anatomical context of ABP1

• A genomic clone encoding an auxin-binding protein (ABP) from the endoplasmic reticulum was isolated from Arabidopsis thaliana [4].
• The auxin signal for protoplast swelling is perceived by extracellular ABP1 [7].
• Of several auxin-binding systems that have been characterised the auxin-binding protein (ABP) of maize coleoptile membranes is the best candidate for a true auxin receptor [6].

Analytical, diagnostic and therapeutic context of ABP1

• The latter antibodies have been used in a sandwich ELISA to demonstrate that auxin binding induces a conformational change in ABP [6].

References