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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

RAC3  -  Rac-like GTP-binding protein ARAC3

Arabidopsis thaliana

Synonyms: ARAC3, ATROP6, M4E13.80, M4E13_80, RAC-like 3, ...
 
 
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High impact information on ARAC3/ATROP6/RHO1PS/ROP6

  • Resistance to Albugo candida isolate Acem1 is conferred by a dominant gene, RAC1, in accession Ksk-1 of Arabidopsis thaliana [1].
  • Microscopic analysis of transiently transfected BY2 cells revealed a predominant localization of AtROP4 in the perinuclear region, while AtROP6 was localized almost exclusively to the plasma membrane [2].
  • RAC1 was mapped to the top arm of chromosome 1 in the 1 cM interval between RFLP markers M254 and M253 [3].
  • The deduced amino acid sequence of the Brac1 protein is closely related to that of Arabidopsis thaliana Arac3 (91%), but it shares relatively little homology with other members of the Ras superfamily (about 30% identity) [4].

References

  1. The arabidopsis TIR-NB-LRR gene RAC1 confers resistance to Albugo candida (white rust) and is dependent on EDS1 but not PAD4. Borhan, M.H., Holub, E.B., Beynon, J.L., Rozwadowski, K., Rimmer, S.R. Mol. Plant Microbe Interact. (2004) [Pubmed]
  2. Localization of AtROP4 and AtROP6 and interaction with the guanine nucleotide dissociation inhibitor AtRhoGDI1 from Arabidopsis. Bischoff, F., Vahlkamp, L., Molendijk, A., Palme, K. Plant Mol. Biol. (2000) [Pubmed]
  3. Phenotypic and genotypic variation in the interaction between Arabidopsis thaliana and Albugo candida. Holub, E.B., Brose, E., Tör, M., Clay, C., Crute, I.R., Beynon, J.L. Mol. Plant Microbe Interact. (1995) [Pubmed]
  4. A rac-like small G-protein from Brassica campestris activates a PKC-dependent phospholipase D. Kim, H., Nahm, M., Lim, C., Yun, D., Cho, M., Bahk, J. Phytochemistry (2004) [Pubmed]
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