High impact information on SEN1

• SAG101, a leaf senescence-associated gene, was cloned from an Arabidopsis leaf senescence enhancer trap line and functionally characterized [1].
• RNA gel blot analysis revealed that increased expression of senescence-associated genes is preceded by declines in photosynthesis and in the expression of photosynthesis-associated genes [2].
• A comparative transcriptome analysis for successive stages of Arabidopsis (Arabidopsis thaliana) developmental leaf senescence (NS), darkening-induced senescence of individual leaves attached to the plant (DIS), and senescence in dark-incubated detached leaves (DET) revealed many novel senescence-associated genes with distinct expression profiles [3].
• Here, we show that CCR-LIKE (CCL) and SENESCENCE ASSOCIATED GENE 1 transcripts are differentially regulated at the level of mRNA stability at different times of day [4].
• Senescence-associated vacuoles with intense proteolytic activity develop in leaves of Arabidopsis and soybean [5].

Biological context of SEN1

• Senescence-associated genes SEN1 and YSL4 were up-regulated in atapg9-1 before induction of senescence, unlike in wild type [6].
• Examination of the expression patterns of the sen1 gene under various senescing conditions along with measurements of photochemical efficiency and of chlorophyll content revealed that the sen1 gene expression is associated with Arabidopsis leaf senescence [7].
• Ultraviolet-B exposure leads to up-regulation of senescence-associated genes in Arabidopsis thaliana [8].
• Analysis of transgenic plants expressing the SEN1 promoter fused to uidA reporter gene confirmed the responsiveness of the SEN1 promoter to defence- and senescence-associated signals [9].
• Phylogeny analysis suggested that GmRLCK was more close to and might have a common ancestor with several senescence-associated RLKs [10].

Associations of SEN1 with chemical compounds

• The encoded peptide shows noticeable similarity to the bacterial sulfide dehydrogenase and 81% identity to the peptide encoded by the radish din1 gene [7].
• Expression of the sen1 gene was also strongly induced in leaves subjected to senescence by 0.1mM abscisic acid or 1 mM ethephon treatment [7].
• In addition, the vtc1 mutant exhibits elevated levels of some senescence-associated gene (SAG) transcripts as well as heightened salicylic acid levels [11].
• It is, however, leaf senescence-associated, and the other Cys proteinases are <52% identical [12].
• Two MYB transcription factor genes, PAP1 and PAP2, were identified as senescence-associated genes that are induced by glucose [13].

Regulatory relationships of SEN1

• Response to darkness of late-responsive dark-inducible genes is positively regulated by leaf age and negatively regulated by calmodulin-antagonist-sensitive signalling in Arabidopsis thaliana [14].

Other interactions of SEN1

• These observations imply that VRN1 may promote RNA degradation during senescence of somatic cells in V. carteri, and that its regulation has similarity with that of certain senescence-associated RNases in higher plants [15].

References