High impact information on AHK2

• Together, the analyses reveal partially redundant functions of the cytokinin receptors and prominent roles for the AHK2/AHK3 receptor combination in quantitative control of organ growth in plants, with opposite regulatory functions in roots and shoots [1].
• The growth and development of the ahk2 ahk3 ahk4 triple mutant were markedly inhibited in various tissues and organs, including the roots and leaves in the vegetative growth phase and the influorescence meristem in the reproductive phase [2].
• We identified three novel, highly homologous, sensor histidine kinases that possibly function in the plasma membrane of Arabidopsis thaliana, i.e. AHK2, 3 and 4 [3].
• We previously identified a set of structurally related genes, AHK2, 3 and 4, each encoding a sensor histidine kinase in Arabidopsis thaliana [4].

Biological context of AHK2

• The ahk2 ahk4 and ahk3 ahk4 double mutants and the ahk single mutants grew normally, whereas the ahk2 ahk3 double mutants exhibited a semidwarf phenotype as to shoots, such as a reduced leaf size and a reduced influorescence stem length [2].

Other interactions of AHK2

• Conversely, replacing CRE1 with AHK2, which favors kinase activity, increased cytokinin sensitivity [5].

References