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Gene Review

BR6OX1  -  brassinosteroid-6-oxidase 1

Arabidopsis thaliana

Synonyms: ATBR6OX, BR6OX, BRASSINOSTEROID-6-OXIDASE, CYP85A1, K15E6.150, ...
 
 
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Disease relevance of BR6OX1

  • A null mutation in the tomato Dwarf (CYP85A1) gene, extreme dwarf (d(x)), causes severe dwarfism due to brassinosteroid deficiency, but the d(x) mutant still produces fruits [1].
 

High impact information on BR6OX1

 

Biological context of BR6OX1

References

  1. The last reaction producing brassinolide is catalyzed by cytochrome P-450s, CYP85A3 in tomato and CYP85A2 in Arabidopsis. Nomura, T., Kushiro, T., Yokota, T., Kamiya, Y., Bishop, G.J., Yamaguchi, S. J. Biol. Chem. (2005) [Pubmed]
  2. Arabidopsis CYP85A2, a cytochrome P450, mediates the Baeyer-Villiger oxidation of castasterone to brassinolide in brassinosteroid biosynthesis. Kim, T.W., Hwang, J.Y., Kim, Y.S., Joo, S.H., Chang, S.C., Lee, J.S., Takatsuto, S., Kim, S.K. Plant Cell (2005) [Pubmed]
  3. Unique and overlapping expression patterns of Arabidopsis CYP85 genes involved in brassinosteroid C-6 oxidation. Castle, J., Szekeres, M., Jenkins, G., Bishop, G.J. Plant Mol. Biol. (2005) [Pubmed]
 
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