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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SAD1  -  U6 snRNA-associated Sm-like protein LSM5

Arabidopsis thaliana

Synonyms: AtLSM5, AtSAD1, K24G6.21, K24G6_21, LSM5, ...
 
 
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High impact information on SAD1

  • Analysis of RD29A:LUC luminescence and ABA and stress sensitivity in double mutants of sad2-1 and sad1 or abh1-7, a newly isolated allele of ABH1 also in the RD29A:LUC background, suggested that SAD2 acts upstream of or has additive effects with these two genes [1].
 

Biological context of SAD1

 

Associations of SAD1 with chemical compounds

  • These data provide evidence for the model that the mRNA-processing proteins ABH1 and SAD1 function as negative regulators in guard cell ABA signaling [2].
 

Analytical, diagnostic and therapeutic context of SAD1

  • Validation of a cotton-specific gene, Sad1, used as an endogenous reference gene in qualitative and real-time quantitative PCR detection of transgenic cottons [3].
  • The results of Southern blot analysis also showed that the Sad1 gene was two copies in these 15 different G. hirsutum cultivars [3].

References

  1. Mutation of SAD2, an importin beta-domain protein in Arabidopsis, alters abscisic acid sensitivity. Verslues, P.E., Guo, Y., Dong, C.H., Ma, W., Zhu, J.K. Plant J. (2006) [Pubmed]
  2. Localization, ion channel regulation, and genetic interactions during abscisic acid signaling of the nuclear mRNA cap-binding protein, ABH1. Hugouvieux, V., Murata, Y., Young, J.J., Kwak, J.M., Mackesy, D.Z., Schroeder, J.I. Plant Physiol. (2002) [Pubmed]
  3. Validation of a cotton-specific gene, Sad1, used as an endogenous reference gene in qualitative and real-time quantitative PCR detection of transgenic cottons. Yang, L., Chen, J., Huang, C., Liu, Y., Jia, S., Pan, L., Zhang, D. Plant Cell Rep. (2005) [Pubmed]
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