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Gene Review

PFC1  -  dimethyladenosine transferase

Arabidopsis thaliana

Synonyms: DIMETHYLADENOSINE TRANSFERASE, PALEFACE 1
 
 
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Disease relevance of PFC1

  • Wild-type Arabidopsis expressing antisense constructs of PFC1 grew normally at 22 degrees C but showed chilling-induced chlorosis, confirming that the gene is essential for low-temperature development of chloroplasts [1].
 

High impact information on PFC1

  • The deduced amino acid sequence of PFC1 has identity with rRNA methylases found in bacteria and yeast that modify specific adenosines of pre-rRNA transcripts [1].
  • The pfc1 mutant does not have these modifications in the small subunit rRNA of the plastid [1].

References

 
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