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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PHV  -  homeobox-leucine zipper protein ATHB-9

Arabidopsis thaliana

Synonyms: ATHB9, F26G16.11, F26G16_11, PHAVOLUTA
 
 
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High impact information on PHV

  • Role of PHABULOSA and PHAVOLUTA in determining radial patterning in shoots [1].
  • They do so by altering the predicted sterol/lipid-binding domains of ATHB14 and ATHB9, proteins of previously unknown function that also contain DNA-binding motifs [1].
  • PHB, PHV and REV transcripts contain a complementary site for miRNA165 and miRNA166, which can direct their cleavage in vitro [2].
 

Biological context of PHV

  • We show that PHB and PHV coding sequences are heavily methylated downstream of the microRNA complementary site in most wild-type plant cells and that methylation is reduced in phb-1d and phv-1d mutants [3].

References

  1. Role of PHABULOSA and PHAVOLUTA in determining radial patterning in shoots. McConnell, J.R., Emery, J., Eshed, Y., Bao, N., Bowman, J., Barton, M.K. Nature (2001) [Pubmed]
  2. microRNA-mediated repression of rolled leaf1 specifies maize leaf polarity. Juarez, M.T., Kui, J.S., Thomas, J., Heller, B.A., Timmermans, M.C. Nature (2004) [Pubmed]
  3. MicroRNA binding sites in Arabidopsis class III HD-ZIP mRNAs are required for methylation of the template chromosome. Bao, N., Lye, K.W., Barton, M.K. Dev. Cell (2004) [Pubmed]
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