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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PRS2  -  ribose-phosphate pyrophosphokinase 2

Arabidopsis thaliana

Synonyms: F5D14.15, F5D14_15, phosphoribosyl pyrophosphate (PRPP) synthase 2
 
 
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Disease relevance of AT1G32380

  • PRS2 is a resistance gene of Arabidopsis thaliana that confers resistance against Pseudomonas syringae bacteria that express avirulence gene avrRpt2 [1].
 

High impact information on AT1G32380

  • PRS2 mRNA levels increased twofold in roots and shoots of P-starved plants, while PRS3 was constitutively-expressed [2].
 

Associations of AT1G32380 with chemical compounds

  • Expression of P-dependent and P-independent phosphoribosyl pyrophosphate (PRPP) synthases (PRS2 and PRS3, respectively) which provide PRPP, the phosphoribosyl donor in UMP synthesis via both de novo and salvaging pathways, was differentially regulated in response to P limitation [2].

References

  1. RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of plant disease resistance genes. Bent, A.F., Kunkel, B.N., Dahlbeck, D., Brown, K.L., Schmidt, R., Giraudat, J., Leung, J., Staskawicz, B.J. Science (1994) [Pubmed]
  2. Effects of phosphate limitation on expression of genes involved in pyrimidine synthesis and salvaging in Arabidopsis. Hewitt, M.M., Carr, J.M., Williamson, C.L., Slocum, R.D. Plant Physiol. Biochem. (2005) [Pubmed]
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