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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

GFM2  -  G elongation factor, mitochondrial 2

Homo sapiens

Synonyms: EF-G2mt, EFG2, Elongation factor G 2, mitochondrial, Elongation factor G2, FLJ21661, ...
 
 
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High impact information on GFM2

  • Identification and characterization of two novel human mitochondrial elongation factor genes, hEFG2 and hEFG1, phylogenetically conserved through evolution [1].
  • We have used a combined biochemical and computer-based approach to characterize a 146 kb human genomic bacterial artificial chromosome clone from chromosome 5q13 and discovered a novel human elongation-factor gene, hEFG2 [1].
  • The complete human EFG2 cDNA sequence is 3033 bp and contains 21 exons with conserved exon-intron splice junctions encompassing 45 kb of the genomic sequence with its 5'-end residing within a CpG island, characteristic of a housekeeping gene [1].

References

  1. Identification and characterization of two novel human mitochondrial elongation factor genes, hEFG2 and hEFG1, phylogenetically conserved through evolution. Hammarsund, M., Wilson, W., Corcoran, M., Merup, M., Einhorn, S., Grandér, D., Sangfelt, O. Hum. Genet. (2001) [Pubmed]
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