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Gene Review:

AT1G79470 - inosine-5'-monophosphate dehydrogenase

Arabidopsis thaliana

Synonyms: T8K14.11, T8K14_11

Collart, F.R. et al., Ermolayev, V. et al., Cao, Y. et al.

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High impact information on AT1G79470

The putative active-site sequence of At IMPDH conforms to the IMP dehydrogenase/guanosine monophosphate reductase motif and contains an essential active-site cysteine residue [1].
The deduced IMPDH amino-acid sequence from At shows a remarkable similarity to other eukaryotic IMPDH sequences, with a 48% identity to human Type II enzyme [1].
Formation of numerous lateral roots in transgenic plants with low elicited callose accumulation under stress conditions indicated ability of the IMPDH homologue to mediate aluminium tolerance in transgenic plants [2].

Analytical, diagnostic and therapeutic context of AT1G79470

Molecular cloning and characterization of a cDNA encoding soybean nodule IMP dehydrogenase [3].

References

Cloning and characterization of the gene encoding IMP dehydrogenase from Arabidopsis thaliana. Collart, F.R., Osipiuk, J., Trent, J., Olsen, G.J., Huberman, E. Gene (1996) [Pubmed]
Comparison of Al-induced gene expression in sensitive and tolerant soybean cultivars. Ermolayev, V., Weschke, W., Manteuffel, R. J. Exp. Bot. (2003) [Pubmed]
Molecular cloning and characterization of a cDNA encoding soybean nodule IMP dehydrogenase. Cao, Y., Schubert, K.R. Biochim. Biophys. Acta (2001) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

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AT1G16350	Arabidopsis thaliana
AGOS_AER117W	Ashbya gossypii ATCC 10895
IMPDH1	Bos taurus
T22D1.3	Caenorhabditis elegans
IMPDH1	Canis lupus familiaris
impdh1a	Danio rerio
impdh1b	Danio rerio
ras	Drosophila melanogaster
IMPDH1	Homo sapiens
KLLA0B05511g	Kluyveromyces lactis NRRL Y-1140
LOC701039	Macaca mulatta
MGG_03699	Magnaporthe oryzae 70-15
Impdh1	Mus musculus
NCU03117	Neurospora crassa OR74A
Os03g0780500	Oryza sativa Japonica Group
IMPDH1	Pan troglodytes
Impdh1	Rattus norvegicus
IMD3	Saccharomyces cerevisiae S288c
IMD2	Saccharomyces cerevisiae S288c
IMD4	Saccharomyces cerevisiae S288c
gua1	Schizosaccharomyces pombe 972h-
impdh1	Xenopus (Silurana) tropicalis

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