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Gene Review

TED3  -  peroxin-2

Arabidopsis thaliana

Synonyms: ARABIDOPSIS PEROXIN 2, ATPEX2, F20B17.23, F20B17_23, PEROXIN 2, ...
 
 
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High impact information on TED3

  • AtPEX2 and AtPEX10 are targeted to peroxisomes independently of known endoplasmic reticulum trafficking routes [1].
  • We conclude that AtPEX2 and AtPEX10 are inserted into peroxisome membranes directly from the cytosol [1].
  • TED1, TED2 and TED3 are newly described genes, whose function appears closely associated with that of DET1 [2].
  • Transgenic Arabidopsis plants with a chimeric gene of the 537 bp TED3 promoter and the beta-glucuronidase (GUS) reporter gene indicated the strong expression of the GUS gene by the TED3 promoter in TEs, in particular in immature TEs as well as stipules and trichomes [3].
  • To determine the regulatory mechanism of gene expression in the early stages of tracheary element (TE) differentiation, we isolated and characterized a genomic fragment of TED3 whose mRNA is expressed preferentially in differentiating TEs 12-24 h before morphological changes in the in vitro Zinnia system [3].
 

Biological context of TED3

  • We have identified the molecular lesion in ted3, a mutation that dominantly suppresses the phenotypes of det1-1 [4].
 

Associations of TED3 with chemical compounds

  • Blocking known ER transport routes using the fungal metabolite Brefeldin A or expressing dominant negative mutants of Sar1 or RabD2a had no effect on the trafficking of AtPEX2 and AtPEX10 to peroxisomes [1].
 

Analytical, diagnostic and therapeutic context of TED3

References

 
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