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GPR123  -  G protein-coupled receptor 123

Homo sapiens

Synonyms: KIAA1828
 
 
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High impact information on GPR123

  • The CNS specific expression, together with the high sequence conservation between the vertebrate sequences investigated, indicate that GPR123 may have an important role in the regulation of neuronal signal transduction [1].
  • The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells [1].
 

Analytical, diagnostic and therapeutic context of GPR123

  • The real-time PCR data indicates that GPR123 is predominantly expressed in CNS [1].
  • We report the evolutionary history of the Adhesion family protein GPR123 as well as mapping of GPR123 mRNA expression in mouse and rat using in situ hybridization and real-time PCR, respectively [1].

References

  1. The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells. Lagerström, M.C., Rabe, N., Haitina, T., Kalnina, I., Hellström, A.R., Klovins, J., Kullander, K., Schiöth, H.B. J. Neurochem. (2007) [Pubmed]
 
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