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Gene Review: 

FRM2  -  Frm2p

Saccharomyces cerevisiae S288c

Synonyms: Fatty acid repression mutant protein 2, YCL026C-A, YCLX08C, YCLX8C
 
 
 
 
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High impact information on FRM2

  • The upstream region of FRM2 contained a number of potential response elements which have previously been identified as important in regulating gene expression in response to glucose and certain fatty acids [1].
  • POX1 has been shown to be transcriptionally activated in the presence of unsaturated fatty acids. frm2 was rescued by a region of DNA localized to chromosome III [1].

References

  1. Identification of a class of Saccharomyces cerevisiae mutants defective in fatty acid repression of gene transcription and analysis of the frm2 gene. McHale, M.W., Kroening, K.D., Bernlohr, D.A. Yeast (1996) [Pubmed]
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