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Gene Review

SAP155  -  Sap155p

Saccharomyces cerevisiae S288c

Synonyms: SIT4-associating protein SAP155, YFR040W
 
 
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High impact information on SAP155

  • Nevertheless, overexpression of certain Cct subunits, especially CCT6, suppresses a wide range of abnormal phenotypes, including those caused by the diverse types of conditional mutations tor2-21, lst8-2 and rsp5-9 and those caused by the concomitant overexpression of Sit4p and Sap155p [1].
  • In contrast, a homolog of SAP155, called SAP185, encodes a positive modulator of K+ efflux: overexpression of SAP185 increases efflux, whereas deletion decreases efflux [2].

References

  1. Physiological effects of unassembled chaperonin Cct subunits in the yeast Saccharomyces cerevisiae. Kabir, M.A., Kaminska, J., Segel, G.B., Bethlendy, G., Lin, P., Della Seta, F., Blegen, C., Swiderek, K.M., Zoładek, T., Arndt, K.T., Sherman, F. Yeast (2005) [Pubmed]
  2. Ability of Sit4p to promote K+ efflux via Nha1p is modulated by Sap155p and Sap185p. Manlandro, C.M., Haydon, D.H., Rosenwald, A.G. Eukaryotic Cell (2005) [Pubmed]
 
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