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Gene Review

EMP46  -  Emp46p

Saccharomyces cerevisiae S288c

Synonyms: 46 kDa endomembrane protein, Protein EMP46, YLR080W
 
 
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High impact information on EMP46

  • Structures of the carbohydrate recognition domain of Ca2+-independent cargo receptors Emp46p and Emp47p [1].
  • Furthermore, the CRD of Emp46p binds to glycoproteins carrying high mannosetype glycans and the is promoted by binding not the addition of Ca(2+) or K(+) ion in These results suggest that Emp46p can be regarded as a Ca(2+)-independent intracellular lectin at the ER exit sites [1].
  • When the proteoliposomes were mixed with COPII proteins and GMP-PNP, Emp46/47p, but not Ufe1p, were concentrated into COPII vesicles [2].
  • On block of forward transport in sec12-4 cells, redistribution of Emp46p from the Golgi to the endoplasmic reticulum is observed [3].
  • The C-terminal tail of Emp46p includes a dilysine signal [3].
 

Biological context of EMP46

 

Anatomical context of EMP46

  • Recombinant Emp46/47p proteins and the ER resident protein Ufe1p were reconstituted into liposomes whose composition resembles yeast ER membranes [2].
 

Associations of EMP46 with chemical compounds

References

 
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