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Gene Review:

PEX32 - Pex32p

Saccharomyces cerevisiae S288c

Synonyms: Peroxin-32, Peroxisomal membrane protein PEX32, YBR1220, YBR168W

Vizeacoumar, F.J. et al., Vizeacoumar, F.J. et al.

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High impact information on PEX32

Pex30p and Pex32p control peroxisome size and number but are dispensable for peroxisome formation [1].
Both Pex30p and Pex32p interact with Pex19p in regions that do not overlap with their PTSs [1].
Systematic truncations from the carboxyl terminus, together with in-frame deletions of specific regions, have identified PTSs essential for targeting Pex30p and Pex32p to peroxisomes [1].
Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae [2].

Biological context of PEX32

Mutants of Pex30p and Pex32p that localize to peroxisomes but produce cells exhibiting the peroxisomal phenotypes of cells lacking these proteins demonstrate that the regions in these proteins that control peroxisomal targeting and cell biological activity are separable [1].

Other interactions of PEX32

Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals [1].

References

Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals. Vizeacoumar, F.J., Vreden, W.N., Aitchison, J.D., Rachubinski, R.A. J. Biol. Chem. (2006) [Pubmed]
Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae. Vizeacoumar, F.J., Torres-Guzman, J.C., Bouard, D., Aitchison, J.D., Rachubinski, R.A. Mol. Biol. Cell (2004) [Pubmed]

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AGOS_AGR215C	Ashbya gossypii ATCC 10895
KLLA0E24641g	Kluyveromyces lactis NRRL Y-1140

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