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Gene Review: 

BUD13  -  Bud13p

Saccharomyces cerevisiae S288c

Synonyms: Bud site selection protein 13, CWC26, Complexed with CEF1 protein 26, G1642, Pre-mRNA-splicing factor CWC26, ...
 
 
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High impact information on BUD13

  • TAP purification revealed that Snu17p, together with Bud13p and a newly identified factor, Pml1p/Ylr016c, form a novel trimeric complex [1].
  • In addition to known genes, we found 22 novel genes (20 are designated BUD13-BUD32) important for bud site selection [2].
  • A subset of Mer1p-dependent introns requires Bud13p for splicing activation and nuclear retention [3].
  • ORF G1642 shares some identity with a hypothetical protein of Caenorhabditis elegans, while the other four ORFs show no significant homology to known proteins [4].

References

  1. Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing. Dziembowski, A., Ventura, A.P., Rutz, B., Caspary, F., Faux, C., Halgand, F., Laprévote, O., Séraphin, B. EMBO J. (2004) [Pubmed]
  2. A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Ni, L., Snyder, M. Mol. Biol. Cell (2001) [Pubmed]
  3. A subset of Mer1p-dependent introns requires Bud13p for splicing activation and nuclear retention. Scherrer, F.W., Spingola, M. RNA (2006) [Pubmed]
  4. The sequence of an 11.1 kb fragment on the left arm of Saccharomyces cerevisiae chromosome VII reveals six open reading frames including NSP49, KEM1 and four putative new genes. Bertani, I., Coglievina, M., Zaccaria, P., Klima, R., Bruschi, C.V. Yeast (1995) [Pubmed]
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