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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SGF73  -  Sgf73p

Saccharomyces cerevisiae S288c

Synonyms: 73 kDa SAGA-associated factor, SAGA histone acetyltransferase complex 73 kDa subunit, SAGA-associated factor 73, YGL066W
 
 
 
 
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High impact information on SGF73

  • Similarly, Sgf73p facilitates PIC formation at another SAGA-dependent gene, ADH1, independent of histone H3 acetylation or HAT [1].
  • In contrast, Sgf73p stimulates PIC formation at PHO84 (a SAGA-dependent gene), in a HAT-dependent-manner [1].
  • Here, using a chromatin immunoprecipitation (ChIP) assay, we show in vivo that, like SAGA, Sgf73p is recruited to the upstream activating sequence (UAS) of a SAGA-dependent gene, GAL1, in an activator-dependent manner [1].

References

  1. SAGA-associated Sgf73p facilitates formation of the preinitiation complex assembly at the promoters either in a HAT-dependent or independent manner in vivo. Shukla, A., Bajwa, P., Bhaumik, S.R. Nucleic Acids Res. (2006) [Pubmed]
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