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Gene Review

NMD5  -  Nmd5p

Saccharomyces cerevisiae S288c

Synonyms: J2112, KAP119, Karyopherin-119, Nonsense-mediated mRNA decay protein 5, YJR132W
 
 
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High impact information on NMD5

  • Calcineurin-dependent nuclear import of the transcription factor Crz1p requires Nmd5p [1].
  • We also demonstrate that the binding of Crz1p to Nmd5p is dependent upon its phosphorylation state, indicating that nuclear import of Crz1p is regulated by calcineurin [1].
  • Rather, HOG1 import requires the activity of a gene, NMD5, that encodes a novel importin beta homolog [2].
  • Likewise, docking of the carrier Nmd5p at the nuclear pore is enhanced by ethanol [3].
  • AlcR can be imported into nuclei via multiple transport pathways mediated by a distinct set of karyopherins composed of Kap104p, Sxm1p, and Nmd5p transport receptors [4].
 

Associations of NMD5 with chemical compounds

  • Ethanol treatment significantly increases the formation of import complexes containing Nmd5p and the N-terminal Ssa4p domain [3].

References

 
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