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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

DPH2  -  Dph2p

Saccharomyces cerevisiae S288c

Synonyms: Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, YKL191W
 
 
 
 
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Disease relevance of DPH2

  • Loss of YIL103w and DPH2 (involved in diphtheria toxicity) suppresses zymocicity implying that both toxins overlap in a manner mediated by Kti11p [1].

References

  1. Elongator's toxin-target (TOT) function is nuclear localization sequence dependent and suppressed by post-translational modification. Fichtner, L., Jablonowski, D., Schierhorn, A., Kitamoto, H.K., Stark, M.J., Schaffrath, R. Mol. Microbiol. (2003) [Pubmed]
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