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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

REX4  -  Rex4p

Saccharomyces cerevisiae S288c

Synonyms: RNA exonuclease 4, YOL080C
 
 
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High impact information on REX4

  • The RNA catabolic enzymes Rex4p, Rnt1p, and Dbr1p show genetic interaction with trans-acting factors involved in processing of ITS1 in Saccharomyces cerevisiae pre-rRNA [1].
  • The sl phenotype of the rrp5Delta/rex4(-) double mutants appears to be due to a severe disturbance in ribosomal subunit assembly, rather than pre-rRNA processing [2].
  • Furthermore, they clearly implicate Rex4p in both pre-rRNA processing and ribosome assembly, even though this protein is not essential for yeast [2].

References

  1. The RNA catabolic enzymes Rex4p, Rnt1p, and Dbr1p show genetic interaction with trans-acting factors involved in processing of ITS1 in Saccharomyces cerevisiae pre-rRNA. Faber, A.W., Vos, J.C., Vos, H.R., Ghazal, G., Elela, S.A., Raué, H.A. RNA (2004) [Pubmed]
  2. Deletions in the S1 domain of Rrp5p cause processing at a novel site in ITS1 of yeast pre-rRNA that depends on Rex4p. Eppens, N.A., Faber, A.W., Rondaij, M., Jahangir, R.S., van Hemert, S., Vos, J.C., Venema, J., Raué, H.A. Nucleic Acids Res. (2002) [Pubmed]
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