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Gene Review

AKR2  -  Akr2p

Saccharomyces cerevisiae S288c

Synonyms: Ankyrin repeat-containing protein AKR2, OR26.25, YOR034C
 
 
 
 
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High impact information on AKR2

  • Although Akr2 is highly homologous to Akr1, the deletion of AKR2 did not result in any remarkable phenotypes [1].
  • However, overproduction of Akr2 resulted in reduced amounts of Lcb4 [1].
  • We demonstrated that Akr2 is an unstable protein and is degraded in the vacuole [1].

References

  1. Long-chain base kinase Lcb4 Is anchored to the membrane through its palmitoylation by Akr1. Kihara, A., Kurotsu, F., Sano, T., Iwaki, S., Igarashi, Y. Mol. Cell. Biol. (2005) [Pubmed]
 
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