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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

TPO4  -  Tpo4p

Saccharomyces cerevisiae S288c

Synonyms: O5440, Polyamine transporter 4, YOR273C
 
 
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High impact information on TPO4

  • In Saccharomyces cerevisiae four transporters, Tpo1p-Tpo4p, all members of the major facilitator superfamily, have been shown to confer resistance to polyamines [1].
  • Membrane proteins encoded by the open reading frames YGR138c (TPO2), YPR156c (TPO3) and YOR273c (TPO4) were postulated to be polyamine transporters and, indeed, were subsequently shown to be polyamine transport proteins on the vacuolar membrane [2].

References

  1. Localization and function of the yeast multidrug transporter Tpo1p. Albertsen, M., Bellahn, I., Krämer, R., Waffenschmidt, S. J. Biol. Chem. (2003) [Pubmed]
  2. Multiple polyamine transport systems on the vacuolar membrane in yeast. Tomitori, H., Kashiwagi, K., Asakawa, T., Kakinuma, Y., Michael, A.J., Igarashi, K. Biochem. J. (2001) [Pubmed]
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