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Gene Review

THS1  -  threonine--tRNA ligase THS1

Saccharomyces cerevisiae S288c

Synonyms: ThrRS, Threonine--tRNA ligase, cytoplasmic, Threonyl-tRNA synthetase, YIL078W
 
 
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High impact information on THS1

  • A 2,202 nucleotide long open reading frame corresponding to THS1 has been identified in the cloned fragment of DNA [1].
  • However the mutants of group three exhibit a structurally altered ThrRS, which is no longer inhibited by borrelidin [2].
 

Analytical, diagnostic and therapeutic context of THS1

  • To clone THS1, a library was constructed by ligation to pUC18 of size selected (3-4.5 kb) EcoRI fragments of genomic DNA [1].

References

 
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