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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

DJP1  -  Djp1p

Saccharomyces cerevisiae S288c

Synonyms: DnaJ-like protein 1, ICS1, PAS22, Peroxisome assembly protein 22, YIB4W, ...
 
 
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Disease relevance of DJP1

 

High impact information on DJP1

  • Furthermore, the metabolic adaptation to a change in carbon source, a complex multistep process, was unaffected in a DJP1 gene deletion mutant [1].
  • Cells with a DJP1 gene deletion are viable and exhibit a novel phenotype among cytosolic J-protein mutants in that they have a specific impairment of only one organelle, the peroxisome [1].
  • The pas (peroxisome assembly) mutants that have been used for complementation analysis represent 12 complementation groups including three novel ones, designated pas20, pas21 and pas22 [2].

References

  1. The cytosolic DnaJ-like protein djp1p is involved specifically in peroxisomal protein import. Hettema, E.H., Ruigrok, C.C., Koerkamp, M.G., van den Berg, M., Tabak, H.F., Distel, B., Braakman, I. J. Cell Biol. (1998) [Pubmed]
  2. An efficient positive selection procedure for the isolation of peroxisomal import and peroxisome assembly mutants of Saccharomyces cerevisiae. Elgersma, Y., van den Berg, M., Tabak, H.F., Distel, B. Genetics (1993) [Pubmed]
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